Granja C, Faraldo S, Laguna P, Góis L
Unidad de Cuidados Intensivos Polivalente Hospital Pedro Hispano, 4450 Matosinhos, Portugal.
Rev Esp Anestesiol Reanim. 2002 Mar;49(3):137-40.
To study the development of tracheal stenosis after endotracheal intubation, percutaneous tracheotomy or both; to assess risk factors for tracheal stenosis and the relation of risk to endotracheal cuff pressure.
A prospective study enrolling patients sustaining endotracheal intubation longer than 8 hours and/or undergoing percutaneous tracheotomy. Cuff pressure was recorded at the moment of intubation and every 8 hours thereafter; a ceiling of 25 mm Hg was targeted. The patients were examined 6 months after discharge.
Sixteen percutaneous tracheotomies were performed in the 95 patients enrolled (58 men, 37 women). The mean age was 54.1 +/- 19.7 years. The mean APACHE II score for all patients was 16.3 +/- 7.7 and the mean intubation time was 7.3 +/- 11 days, whereas the respective means for patients undergoing percutaneous tracheotomy were 18.4 +/- 7.6 and 20.5 +/- 19 days. Six months after discharge, 55 patients were examined for laryngotracheal lesions by fiberoptic endoscopy. Twenty-three of the remaining patients had died, 7 were lost to follow-up and 10 were only interviewed by telephone. Fiberoptic laryngotracheal endoscopy revealed minimal scarring and reduction of the endotracheal lumen. Reduction of the lumen was observed only in patients who had undergone percutaneous tracheotomy.
Monitoring cuff pressure three times per day seems to contribute to preventing ischemic lesions and tracheal stenosis.
研究气管插管、经皮气管切开术或两者兼施后气管狭窄的发展情况;评估气管狭窄的危险因素以及危险因素与气管内套管压力的关系。
一项前瞻性研究,纳入气管插管时间超过8小时和/或接受经皮气管切开术的患者。在插管时及之后每8小时记录套管压力;目标上限为25毫米汞柱。患者出院后6个月接受检查。
95名纳入患者(58名男性,37名女性)接受了16次经皮气管切开术。平均年龄为54.1±19.7岁。所有患者的急性生理与慢性健康状况评分系统(APACHE II)平均评分为16.3±7.7,平均插管时间为7.3±11天,而接受经皮气管切开术患者的相应平均值分别为18.4±7.6和20.5±19天。出院后6个月,55名患者通过纤维支气管镜检查喉部气管病变。其余23名患者死亡,7名失访,10名仅通过电话访谈。纤维喉镜检查显示瘢痕形成轻微,气管内腔缩小。仅在接受经皮气管切开术的患者中观察到内腔缩小。
每天监测三次套管压力似乎有助于预防缺血性病变和气管狭窄。