表现为离心性环状红斑的自身免疫性孕酮性皮炎：通过体外干扰素-γ释放确认孕酮敏感性
Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-gamma release.
作者信息
Halevy Sima, Cohen Arnon D, Lunenfeld Eitan, Grossman Nili
机构信息
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel.
出版信息
J Am Acad Dermatol. 2002 Aug;47(2):311-3.
Autoimmune progesterone dermatitis was manifested as deep-type erythema annulare centrifugum. Sensitivity to progesterone was studied in vivo by means of intradermal and patch tests, which revealed immediate-type and delayed-type hypersensitivity, respectively. Sensitivity to progesterone was further confirmed in vitro by results of an interferon-gamma release test, which imply a possible role for T(H)1-type cytokines in autoimmune progesterone dermatitis.
自身免疫性孕酮性皮炎表现为深部离心性环状红斑。通过皮内试验和斑贴试验在体内研究了对孕酮的敏感性，结果分别显示为速发型和迟发型超敏反应。干扰素-γ释放试验的结果在体外进一步证实了对孕酮的敏感性，这表明T(H)1型细胞因子在自身免疫性孕酮性皮炎中可能发挥作用。
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