Chan Daniel L, Freeman Lisa M, Labato Mary A, Rush John E
Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA.
J Vet Intern Med. 2002 Jul-Aug;16(4):440-5. doi: 10.1892/0891-6640(2002)016<0440:reoppn>2.3.co;2.
The purpose of this retrospective study was to evaluate the use of partial parenteral nutrition (PPN) in dogs and cats. The medical records of all dogs and cats receiving PPN between 1994 and 1999 were reviewed to determine signalment, reasons for use of PPN, duration of PPN administration, duration of hospitalization, complications, and mortality. Complications were classified as metabolic, mechanical, or septic. One hundred twenty-seven animals (80 dogs and 47 cats) were included in the study, accounting for 443 patient days of PPN. The most common underlying diseases were pancreatitis (n = 41), gastrointestinal disease (n = 33), and hepatic disease (n = 23). Median time of hospitalization before initiation of PPN was 2.8 days (range, 0.2-10.7 days). Median duration of PPN administration was 3.0 days (range, 0.3-8.8 days). Median duration of hospitalization was 7 days (range, 2-20 days). In the 127 animals receiving PPN, 72 complications occurred. These included metabolic (n = 43), mechanical (n = 25), and septic (n = 4) complications. The most common metabolic complication was hyperglycemia (n = 19), followed by lipemia (n = 17) and hyperbilirubinemia (n = 6). Most complications were mild and did not require discontinuation of PPN. Ninety-three (73.2%) of the 127 patients were discharged. All 4 animals with septic complications were discharged from the hospital. The presence, type, and number of complications did not impact the duration of hospitalization or outcome. However, animals that received supplemental enteral nutrition survived more often than those receiving PPN exclusively. Although PPN seems to be a relatively safe method of providing nutritional support, future studies are warranted to determine its efficacy.
这项回顾性研究的目的是评估部分肠外营养(PPN)在犬猫中的应用情况。回顾了1994年至1999年间所有接受PPN的犬猫的病历,以确定动物特征、使用PPN的原因、PPN给药持续时间、住院时间、并发症及死亡率。并发症分为代谢性、机械性或感染性。127只动物(80只犬和47只猫)纳入研究,共计443个PPN患者日。最常见的基础疾病为胰腺炎(n = 41)、胃肠道疾病(n = 33)和肝脏疾病(n = 23)。开始PPN前的中位住院时间为2.8天(范围0.2 - 10.7天)。PPN给药的中位持续时间为3.0天(范围0.3 - 8.8天)。中位住院时间为7天(范围2 - 20天)。在127只接受PPN的动物中,发生了72例并发症。其中包括代谢性并发症(n = 43)、机械性并发症(n = 25)和感染性并发症(n = 4)。最常见的代谢性并发症是高血糖(n = 19),其次是脂血症(n = 17)和高胆红素血症(n = 6)。大多数并发症较轻,无需停止PPN。127例患者中有93例(73.2%)出院。所有4例有感染性并发症的动物均出院。并发症的存在、类型和数量不影响住院时间或结局。然而,接受补充肠内营养的动物比仅接受PPN的动物存活几率更高。尽管PPN似乎是提供营养支持的一种相对安全的方法,但仍需要进一步研究以确定其疗效。