Lippert A C, Fulton R B, Parr A M
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing.
J Vet Intern Med. 1993 Mar-Apr;7(2):52-64. doi: 10.1111/j.1939-1676.1993.tb03170.x.
The records of all dogs and cats receiving total parenteral nutrition (TPN) over a 43-month period were examined retrospectively. Dextrose, amino acids, lipids, electrolytes, and vitamins were administered by central venous catheter according to published nutrient recommendations; 72 dogs and 12 cats were studied, accounting for 380 patient days of TPN. Duration of TPN administration was 1-14 days with a mean of 4.5 days. Most animals required TPN because of gastrointestinal dysfunction, and more than half of them gained weight during TPN administration. Mechanical complications were frequent. Metabolic complications, especially lipid and glucose intolerance, were also commonly seen. Septic complications were the least frequently encountered, but resulted in patient morbidity and may have contributed to mortality. Most animals receiving TPN were returned to enteral nutrition and discharged. For critically ill animals unable to tolerate enteral alimentation, TPN can be supportive therapy in the treatment of the primary disease.
对43个月期间接受全胃肠外营养(TPN)的所有犬猫记录进行回顾性检查。根据已发表的营养建议,通过中心静脉导管给予葡萄糖、氨基酸、脂质、电解质和维生素;研究了72只犬和12只猫,共计380个TPN患者日。TPN给药持续时间为1 - 14天,平均4.5天。大多数动物因胃肠功能障碍需要TPN,其中一半以上在TPN给药期间体重增加。机械并发症很常见。代谢并发症,尤其是脂质和葡萄糖不耐受也很常见。感染性并发症最少见,但导致患者发病,可能与死亡率有关。大多数接受TPN的动物恢复肠内营养并出院。对于无法耐受肠内营养的重症动物,TPN可作为治疗原发性疾病的支持性疗法。