Ho Alice Y, Lopez Adriana S, Eberhart Michael G, Levenson Robert, Finkel Bernard S, da Silva Alexandre J, Roberts Jacquelin M, Orlandi Palmer A, Johnson Caroline C, Herwaldt Barbara L
Philadelphia Department of Public Health, Philadelphia, Pennsylvania 19146, USA.
Emerg Infect Dis. 2002 Aug;8(8):783-8. doi: 10.3201/eid0808.020012.
An outbreak of cyclosporiasis occurred in attendees of a wedding reception held in Philadelphia, Pennsylvania, on June 10, 2000. In a retrospective cohort study, 54 (68.4%) of the 79 interviewed guests and members of the wedding party met the case definition. The wedding cake, which had a cream filling that included raspberries, was the food item most strongly associated with illness (multivariate relative risk, 5.9; 95% confidence interval, 3.6 to 10.5). Leftover cake was positive for Cyclospora DNA by polymerase chain reaction analyses. Sequencing of the amplified fragments confirmed that the organism was Cyclospora cayetanensis. The year 2000 was the fifth year since 1995 that outbreaks of cyclosporiasis definitely or probably associated with Guatemalan raspberries have occurred in the spring in North America. Additionally, this is the second documented U.S. outbreak, and the first associated with raspberries, for which Cyclospora has been detected in the epidemiologically implicated food item.
2000年6月10日，宾夕法尼亚州费城举办了一场婚宴，参加婚宴的人群中爆发了环孢子虫病。在一项回顾性队列研究中，接受访谈的79位宾客及婚礼相关人员中有54人（68.4%）符合病例定义。婚礼蛋糕的奶油馅料中含有树莓，是与疾病关联最密切的食物（多变量相对风险为5.9；95%置信区间为3.6至10.5）。通过聚合酶链反应分析，剩余蛋糕的环孢子虫DNA呈阳性。对扩增片段进行测序证实该病原体为卡耶塔环孢子虫。2000年是自1995年以来北美春季第五年出现明确或可能与危地马拉树莓相关的环孢子虫病暴发。此外，这是美国有记录的第二次暴发，也是首次与树莓相关的暴发，且在流行病学上涉及的食物中检测到了环孢子虫。
Zotero 插件
