Nash G F, Turner L F, Scully M F, Kakkar A K
Imperial College, Hammersmith Hospital, London, UK.
Lancet Oncol. 2002 Jul;3(7):425-30. doi: 10.1016/s1470-2045(02)00789-1.
The presence of platelets in association with cancer deposits has been recognised for over 100 years; however, the recognition of a two-way interaction has been more recent. The link between cancer spread and platelet stimulation is pivotal to understanding of the hypercoagulable state found in most cancer patients. The assistance of platelets in cancer spread may provide opportunities to interrupt this relation, thus inhibiting metastasis.
血小板与癌灶并存已有100多年的历史；然而，对两者双向相互作用的认识则是最近才有的。癌症扩散与血小板刺激之间的联系对于理解大多数癌症患者出现的高凝状态至关重要。血小板在癌症扩散中的作用可能为中断这种关系提供机会，从而抑制转移。
