Van Aggel-Leijssen Dorien P, Saris Wim H, Hul Gabby B, Van Baak Marleen A
Nutrition, Toxicology and Environmental Research Institute (NUTRIM), Department of Human Biology, Maastricht University, Maastricht, The Netherlands.
Metabolism. 2002 Aug;51(8):1003-10. doi: 10.1053/meta.2002.34028.
The aim of the present study was to investigate the effect of long-term continuation of low-intensity exercise training on weight maintenance, substrate metabolism, and beta-adrenergic-mediated fat oxidation in weight-reduced obese men. Preceding this part of the study, subjects lost 15 +/- 6 kg of body weight by energy restriction with or without low-intensity exercise training. Twenty-nine subjects (diet group, n = 15; diet + exercise group, n = 14) participated in the follow-up study of 40 weeks in which the former diet + exercise group continued their exercise training program. Pre- and postfollow-up, measurements of body weight, body composition, maximal aerobic capacity and substrate oxidation during rest, exercise, and recovery with or without infusion of the beta-adrenergic antagonist, propranolol (PRP), were performed. Over the follow-up period, body weight, fat mass, and fat free mass increased in both groups (P <.0001) without differences between groups. Attendance at exercise training sessions was negatively correlated with regain of body weight (r = -.6, P <.05). Relative fat oxidation, energy expenditure, and beta-adrenergic-mediated fat oxidation during rest, exercise, and recovery were maintained over the follow-up period in both groups. Continuation of low-intensity exercise training after weight reduction did not limit regain of body weight, unless exercise training was frequently performed. Relative (beta-adrenergic-mediated) fat oxidation and energy expenditure were maintained at postdiet level whether or not low-intensity exercise training was performed during follow-up.
本研究的目的是调查长期持续进行低强度运动训练对体重减轻后的肥胖男性体重维持、底物代谢以及β-肾上腺素能介导的脂肪氧化的影响。在本研究的这一部分之前，受试者通过能量限制（无论是否进行低强度运动训练）减轻了15±6千克体重。29名受试者（饮食组，n = 15；饮食+运动组，n = 14）参与了为期40周的随访研究，其中之前的饮食+运动组继续其运动训练计划。在随访前后，测量了体重、身体成分、最大有氧能力以及在静息、运动和恢复过程中（无论是否输注β-肾上腺素能拮抗剂普萘洛尔（PRP））的底物氧化情况。在随访期间，两组的体重、脂肪量和去脂体重均增加（P<.0001），两组之间无差异。参加运动训练课程的情况与体重恢复呈负相关（r = -.6，P<.05）。在随访期间，两组在静息、运动和恢复过程中的相对脂肪氧化、能量消耗以及β-肾上腺素能介导的脂肪氧化均得以维持。体重减轻后继续进行低强度运动训练并不会限制体重恢复，除非经常进行运动训练。无论在随访期间是否进行低强度运动训练，相对（β-肾上腺素能介导的）脂肪氧化和能量消耗均维持在节食后的水平。
