Güzel Yasemin, Atakan Muhammed Mustafa, Turnagöl Hüseyin Hüsrev, Koşar Şükran Nazan
Division of Exercise Nutrition and Metabolism, Faculty of Sport Sciences, Hacettepe University, Ankara, Türkiye.
Eur J Clin Nutr. 2025 Apr;79(4):311-319. doi: 10.1038/s41430-024-01546-1. Epub 2024 Nov 23.
Accumulating evidence supports the effectiveness of moderate-intensity aerobic training on metabolic health, with limited studies investigating change in resting substrate oxidation. The aim of this study was to explore whether 10 weeks of walking-based aerobic training would alter substrate oxidation in postmenopausal women with obesity.
Twenty-four postmenopausal women with obesity who were assigned into the control (n = 12) or exercise groups (n = 12) undertook a 10-week aerobic training program (3 d·week) that involved walking exercises at 50-70% of heart rate reserve on a treadmill, with exercise volume increased from 25 to 40 min·day. Resting metabolic rate (RMR) and body composition were measured pre- and post-training. Whole-body substrate oxidation was calculated using respiratory data collected during RMR measurement via indirect calorimetry. No significant change was noted (p > 0.05) in resting fat oxidation and carbohydrate oxidation in the exercise group. Resting respiratory exchange ratio and RMR did not alter in response to the training program (p > 0.05).
Our results show that a 10-week of moderate-intensity aerobic training does not modify substrate oxidation in postmenopausal women with obesity.
越来越多的证据支持中等强度有氧运动训练对代谢健康的有效性，而研究静息底物氧化变化的研究有限。本研究的目的是探讨为期10周的步行有氧运动训练是否会改变肥胖绝经后女性的底物氧化。
24名肥胖绝经后女性被分为对照组（n = 12）或运动组（n = 12），进行为期10周的有氧运动训练计划（每周3天），包括在跑步机上以心率储备的50 - 70%进行步行运动，运动时长从每天25分钟增加到40分钟。在训练前后测量静息代谢率（RMR）和身体成分。通过间接测热法在测量RMR期间收集的呼吸数据计算全身底物氧化。运动组的静息脂肪氧化和碳水化合物氧化没有显著变化（p > 0.05）。静息呼吸交换率和RMR对训练计划没有反应（p > 0.05）。
我们的结果表明，为期10周的中等强度有氧运动训练不会改变肥胖绝经后女性的底物氧化。
