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为期10周的步行运动训练对肥胖绝经后女性静息底物氧化的影响。

Effects of 10 weeks of walking-based exercise training on resting substrate oxidation in postmenopausal women with obesity.

作者信息

Güzel Yasemin, Atakan Muhammed Mustafa, Turnagöl Hüseyin Hüsrev, Koşar Şükran Nazan

机构信息

Division of Exercise Nutrition and Metabolism, Faculty of Sport Sciences, Hacettepe University, Ankara, Türkiye.

出版信息

Eur J Clin Nutr. 2025 Apr;79(4):311-319. doi: 10.1038/s41430-024-01546-1. Epub 2024 Nov 23.

Abstract

BACKGROUND AND AIMS

Accumulating evidence supports the effectiveness of moderate-intensity aerobic training on metabolic health, with limited studies investigating change in resting substrate oxidation. The aim of this study was to explore whether 10 weeks of walking-based aerobic training would alter substrate oxidation in postmenopausal women with obesity.

METHODS AND RESULTS

Twenty-four postmenopausal women with obesity who were assigned into the control (n = 12) or exercise groups (n = 12) undertook a 10-week aerobic training program (3 d·week) that involved walking exercises at 50-70% of heart rate reserve on a treadmill, with exercise volume increased from 25 to 40 min·day. Resting metabolic rate (RMR) and body composition were measured pre- and post-training. Whole-body substrate oxidation was calculated using respiratory data collected during RMR measurement via indirect calorimetry. No significant change was noted (p > 0.05) in resting fat oxidation and carbohydrate oxidation in the exercise group. Resting respiratory exchange ratio and RMR did not alter in response to the training program (p > 0.05).

CONCLUSION

Our results show that a 10-week of moderate-intensity aerobic training does not modify substrate oxidation in postmenopausal women with obesity.

摘要

背景与目的

越来越多的证据支持中等强度有氧运动训练对代谢健康的有效性,而研究静息底物氧化变化的研究有限。本研究的目的是探讨为期10周的步行有氧运动训练是否会改变肥胖绝经后女性的底物氧化。

方法与结果

24名肥胖绝经后女性被分为对照组(n = 12)或运动组(n = 12),进行为期10周的有氧运动训练计划(每周3天),包括在跑步机上以心率储备的50 - 70%进行步行运动,运动时长从每天25分钟增加到40分钟。在训练前后测量静息代谢率(RMR)和身体成分。通过间接测热法在测量RMR期间收集的呼吸数据计算全身底物氧化。运动组的静息脂肪氧化和碳水化合物氧化没有显著变化(p > 0.05)。静息呼吸交换率和RMR对训练计划没有反应(p > 0.05)。

结论

我们的结果表明,为期10周的中等强度有氧运动训练不会改变肥胖绝经后女性的底物氧化。

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