NADPH氧化酶：血管系统中活性氧的新来源？
NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?
作者信息
Van Heerebeek L, Meischl C, Stooker W, Meijer C J L M, Niessen H W M, Roos D
机构信息
Institute of Cardiovascular Research, Free University Medical Center, Amsterdam, The Netherlands.
出版信息
J Clin Pathol. 2002 Aug;55(8):561-8. doi: 10.1136/jcp.55.8.561.
Abstract
Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.
摘要
活性氧在多种（病理）生理血管过程中发挥重要作用。最近的出版物提供了证据，表明假定的非吞噬细胞NADP氧化酶在血管活性氧的产生中起作用。在本综述中，我们讨论了在体外和体内研究中，血管系统中NADP氧化酶不同组分的检测，以及血管NADPH氧化酶产生的活性氧的假定作用。
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