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在实验性牙龈炎期间,评估含或不含防变色系统的洗必泰漱口水与安慰剂相比的抗牙龈炎效果。

Evaluation of the antigingivitis effect of a chlorhexidine mouthwash with or without an antidiscoloration system compared to placebo during experimental gingivitis.

作者信息

Li Wen, Wang Ren E, Finger Martin, Lang Niklaus P

机构信息

Prince Philip Dental Hospital, Faculty of Dentistry, The University of Hong Kong, Sai Ying Pun, Hong Kong.

出版信息

J Investig Clin Dent. 2014 Feb;5(1):15-22. doi: 10.1111/jicd.12050. Epub 2013 Jun 14.

Abstract

AIM

The aim of the present study was to evaluate the effectiveness of chlorhexidine (CHX) with an antidiscoloration system (ADS) on stain, plaque accumulation, and gingivitis.

METHODS

A randomized, controlled clinical trial was conducted in 26 students. After a preparatory period, the students were randomly assigned to either group P (placebo), group T1 (0.12% CHX without an ADS), or group T2 (0.12% CHX with an ADS). During the 3-week experimental period, all mechanical oral hygiene was abolished. Rinsing with 10 mL mouthwash or placebo was performed twice daily under supervision. The parameters assessed on days 0, 7, 14, and 21 included the Discoloration Index (DI), Plaque Index (PII), and Gingival Index (GI).

RESULTS

There were no significant mean differences in the DI, PII, or GI between groups T2 and P. Significant mean differences existed in the DI between groups T2 and T1 on days 14 and 21. Significant mean differences existed in the PI between groups T2 and T1 on days 7, 14, and 21. Likewise, significant mean differences existed in the GI between groups T2 and T1 on days 14 and 21.

CONCLUSIONS

CHX with an ADS did not prevent plaque or gingivitis development. In fact, the CHX mouthwash with an ADS showed no superior effect over placebo on oral hygiene or the prevention of gingivitis.

摘要

目的

本研究旨在评估洗必泰(CHX)与防变色系统(ADS)对牙菌斑、牙菌斑积聚和牙龈炎的疗效。

方法

对26名学生进行了一项随机对照临床试验。在准备期后,学生被随机分为P组(安慰剂组)、T1组(含0.12% CHX但无ADS)或T2组(含0.12% CHX且有ADS)。在为期3周的试验期内,取消了所有机械口腔卫生措施。在监督下,每天两次用10毫升漱口水或安慰剂进行漱口。在第0、7、14和21天评估的参数包括变色指数(DI)、菌斑指数(PII)和牙龈指数(GI)。

结果

T2组和P组之间在DI、PII或GI方面无显著平均差异。在第14天和21天,T2组和T1组之间的DI存在显著平均差异。在第7、14和21天,T2组和T1组之间的PI存在显著平均差异。同样,在第14天和21天,T2组和T1组之间的GI存在显著平均差异。

结论

含ADS的CHX不能预防牙菌斑或牙龈炎的发展。事实上,含ADS的CHX漱口水在口腔卫生或预防牙龈炎方面没有显示出比安慰剂更优越的效果。

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