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梅毒螺旋体特异性抗体免疫层析试纸条检测的初步评估

Preliminary evaluation of an immunochromatographic strip test for specific Treponema pallidum antibodies.

作者信息

Zarakolu Pinar, Buchanan Ian, Tam Milton, Smith Kim, Hook Edward W

机构信息

Section of Infectious Diseases, Department of Medicine, School of Medicine, Hacettepe University, Ankara, Turkey.

出版信息

J Clin Microbiol. 2002 Aug;40(8):3064-5. doi: 10.1128/JCM.40.8.3064-3065.2002.

DOI:10.1128/JCM.40.8.3064-3065.2002
PMID:12149381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC120663/
Abstract

We evaluated a prototype immunochromatographic strip (ICS) test for qualitative detection of Treponema pallidum antibodies in 353 sera from 157 patients. For sera from 43 syphilis patients, the ICSs were reactive, while for sera from 114 patients without syphilis, including 22 with biologically false-positive Rapid Plasma Reagin test results, the ICSs were nonreactive. The ICS test may expand the available options for serological testing for syphilis.

摘要

我们评估了一种用于定性检测157例患者353份血清中梅毒螺旋体抗体的免疫层析试纸条(ICS)检测原型。对于43例梅毒患者的血清,ICS呈阳性反应;而对于114例非梅毒患者的血清,包括22例快速血浆反应素试验结果为生物学假阳性的患者,ICS呈阴性反应。ICS检测可能会增加梅毒血清学检测的可用选项。

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本文引用的文献

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Validation of the INNO-LIA syphilis kit as a confirmatory assay for Treponema pallidum antibodies.验证INNO-LIA梅毒检测试剂盒作为梅毒螺旋体抗体确证试验的有效性。
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