大鼠乳酸脱氢酶的变化：M型和H型乳酸脱氢酶的年龄相关性比较
Alterations in rat lactate dehydrogenase: age-related comparison of M- and H-LDH.
作者信息
Prabhakaram M, Singh S N
出版信息
Biochem Int. 1984 Sep;9(3):399-404.
PMID:6508816
Abstract
Lactate dehydrogenase (LDH: EC 1.1.1.27) of skeletal muscle and heart was purified from young and old female albino rats. Properties of both types, muscle (M-LDH) and heart (H-LDH), were compared by using enzymes purified from skeletal muscle and hearts of young (22-weeks) and old (116-weeks) rats. M-LDH showed differences with respect to properties such as thermal stability and effects of pH, urea, and sodium sulfite. However, H-LDH did not show any significant alterations in enzyme properties.
摘要
从年轻和年老的雌性白化大鼠中纯化出骨骼肌和心脏中的乳酸脱氢酶（LDH：EC 1.1.1.27）。通过使用从年轻（22周）和年老（116周）大鼠的骨骼肌和心脏中纯化的酶，比较了两种类型的酶，即肌肉型（M-LDH）和心脏型（H-LDH）的特性。M-LDH在热稳定性、pH值、尿素和亚硫酸钠的影响等特性方面表现出差异。然而，H-LDH在酶特性方面没有显示出任何显著变化。
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