Kuz'mak N I
Vopr Med Khim. 1975 Sep-Oct;21(5):469-76.
In blood serum of 195 male rats an effect of different thyroid hormones on alterations in content of glycoprotein fractions and their separate carbohydrate containing components was simultaneously studied. A correlation was established between alterations in the glycoprotein fractions and content of seromucoids, sialic acids, hexoses associated with proteins, hexosamine, haptoglobin, transferrin, ceruloplasmin and fucose in blood serum. Dynamics of alterations of these values was studied. The normalization of the tests studied was correlated with the type of hormone used, its dose, duration of the hormone administration and the emotional state of the animals. The mechanisms of alterations in content of the blood glycoproteins, their interrelationship and biosynthesis are discussed.
在195只雄性大鼠的血清中,同时研究了不同甲状腺激素对糖蛋白组分含量变化及其含碳水化合物的单个成分的影响。建立了血清中糖蛋白组分变化与血清类粘蛋白、唾液酸、与蛋白质结合的己糖、氨基己糖、触珠蛋白、转铁蛋白、铜蓝蛋白和岩藻糖含量之间的相关性。研究了这些值变化的动态。所研究测试的正常化与所用激素的类型、剂量、激素给药持续时间以及动物的情绪状态相关。讨论了血液糖蛋白含量变化的机制、它们的相互关系和生物合成。