de Boer Johannes F, Milner Thomas E
Harvard Medical School, Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
J Biomed Opt. 2002 Jul;7(3):359-71. doi: 10.1117/1.1483879.
Polarization sensitive optical coherence tomography (PS-OCT) provides depth resolved measurements of the polarization state of light reflected from turbid media such as tissue. The theory and calculation of the Stokes vector of light reflected from turbid media is described and application of PS-OCT to contemporary biomedical imaging problems is given. Measurement of the depth resolved Stokes parameters allows determination of the degree of polarization and optical axis orientation in turbid media that can be modeled as a linear retarder. Effect of multiple scattering and speckle on the accuracy and noise of the computed Stokes parameters is discussed. Future directions for development of PS-OCT instrumentation for biological and medical applications is given.
偏振敏感光学相干断层扫描(PS-OCT)可对从诸如组织等混浊介质反射的光的偏振态进行深度分辨测量。本文描述了从混浊介质反射的光的斯托克斯矢量的理论和计算,并给出了PS-OCT在当代生物医学成像问题中的应用。对深度分辨斯托克斯参数的测量能够确定混浊介质中的偏振度和光轴方向,该混浊介质可被建模为线性延迟器。文中讨论了多次散射和散斑对计算得到的斯托克斯参数的准确性和噪声的影响。还给出了用于生物和医学应用的PS-OCT仪器的未来发展方向。