de Boer J F, Milner T E, Nelson J S
Opt Lett. 1999 Mar 1;24(5):300-2. doi: 10.1364/ol.24.000300.
Polarization-sensitive optical coherence tomography (PS-OCT) was used to characterize completely the polarization state of light backscattered from turbid media. Using a low-coherence light source, one can determine the Stokes parameters of backscattered light as a function of optical path in turbid media. To demonstrate the application of this technique we determined the birefringence and the optical axis in fibrous tissue (rodent muscle) and in vivo rodent skin. PS-OCT has potentially useful applications in biomedical optics by imaging simultaneously the structural properties of turbid biological materials and their effects on the polarization state of backscattered light. This method may also find applications in material science for investigation of polarization properties (e.g., birefringence) in opaque media such as ceramics and crystals.
偏振敏感光学相干断层扫描(PS-OCT)被用于全面表征从混浊介质反向散射的光的偏振态。使用低相干光源,可以确定混浊介质中反向散射光的斯托克斯参数作为光程的函数。为了证明该技术的应用,我们测定了纤维组织(啮齿动物肌肉)和活体啮齿动物皮肤中的双折射和光轴。PS-OCT通过同时成像混浊生物材料的结构特性及其对反向散射光偏振态的影响,在生物医学光学中具有潜在的有用应用。该方法也可能在材料科学中找到应用,用于研究不透明介质(如陶瓷和晶体)的偏振特性(如双折射)。