Barrett Roseann
Saint Joseph Hospital, Nashua, NH, USA.
Oncol Nurs Forum. 2002 Aug;29(7):1091-8. doi: 10.1188/02.ONF.1091-1098.
PURPOSE/OBJECTIVES: To identify common barriers to the recruitment of participants for oncology clinical trials, identify strategies that would be useful in increasing enrollment of participants in oncology clinical trials, and describe the role of the clinical trial nurse in the recruitment process.
Published articles and abstracts, empirical studies, conference proceedings, references from bibliographies of pertinent articles and books, and computerized databases from 1994-2001.
The barriers to participant recruitment in clinical trials may be categorized as being related to either the patient, healthcare provider, or protocol.
Several achievable strategies for improving recruitment to oncology clinical trials exist. Nurses need to understand the complex and diverse factors that influence participant accrual to oncology clinical trials. Strategies to increase enrollment should focus on increased communications and education for patients and healthcare providers. Dedicated clinical trials nurses can play an integral part in the recruitment and accrual of patients to oncology clinical trials.
Clinical trial nurses play many important roles in the conduct of oncology clinical trials. To better plan and manage these investigations, nurses need to develop strategies to mitigate the complex and diverse factors that may influence accrual patterns.
目的/目标：确定肿瘤学临床试验中招募参与者的常见障碍，确定有助于增加肿瘤学临床试验参与者入组人数的策略，并描述临床试验护士在招募过程中的作用。
1994年至2001年发表的文章和摘要、实证研究、会议记录、相关文章和书籍参考文献中的参考文献以及计算机化数据库。
临床试验中参与者招募的障碍可分为与患者、医疗保健提供者或方案相关的障碍。
存在几种可实现的改善肿瘤学临床试验招募的策略。护士需要了解影响肿瘤学临床试验参与者入组的复杂多样的因素。增加入组人数的策略应侧重于加强对患者和医疗保健提供者的沟通与教育。专门的临床试验护士在肿瘤学临床试验患者的招募和入组中可发挥不可或缺的作用。
临床试验护士在肿瘤学临床试验的开展中发挥着许多重要作用。为了更好地规划和管理这些研究，护士需要制定策略来减轻可能影响入组模式的复杂多样的因素。
