Lefebvre Guylaine, Allaire Catherine, Jeffrey John, Vilos George, Arneja Jagmit, Birch Colin, Fortier Michel
J Obstet Gynaecol Can. 2002 Jan;24(1):37-61; quiz 74-6.
To identify the indications for hysterectomy, preoperative assessment, and available alternatives required prior to hysterectomy. Patient self-reported outcomes of hysterectomy have revealed high levels of patient satisfaction. These may be maximized by careful preoperative assessment and discussion of other treatment choices. In most cases hysterectomy is performed to relieve symptoms and improve quality of life. The patient's preference regarding treatment alternatives must be considered carefully.
The areas of clinical practice considered in formulating this guideline are preoperative assessment including alternative treatments, choice of method for hysterectomy, and evaluation of risks and benefits. The risk-to-benefit ratio must be examined individually by the woman and her health practitioners.
Optimizing the decision-making process of women and their caregivers in proceeding with a hysterectomy having considered the disease process, and available alternative treatments and options, and having reviewed the risks and anticipated benefits.
Using Medline, PubMed, and the Cochrane Database, English language articles were reviewed from 1996 to 2001 as well as the review published in the 1996 SOGC guidelines. The level of evidence has been determined using the criteria described by the Canadian Task Force on the Periodic Health Examination.
BENEFITS, HARMS, AND COSTS: Hysterectomy is the treatment of choice for certain gynaecologic conditions. The predicted advantages must be carefully weighed against the possible risks of the surgery and other treatment alternatives. In the properly selected patient, the result from the surgery should be an improvement in the quality of life. The cost of the surgery to the health care system and to the patient must be interpreted in the context of the cost of untreated conditions. The approach selected for the hysterectomy will impact on the cost of the surgery.
Benign Disease 1. Leiomyomas: For symptomatic fibroids, hysterectomy provides a permanent solution to menorrhagia and the pressure symptoms related to an enlarged uterus. (I-A) 2. Abnormal uterine bleeding: Endometrial lesions must be excluded and medical alternatives should be considered as a first line of therapy. (III-B) 3. Endometriosis: Hysterectomy is often indicated in the presence of severe symptoms with failure of other treatments and when fertility is no longer desired. (1-B) 4. Pelvic relaxation: A surgical solution usually includes vaginal hysterectomy, but must include pelvic supporting procedures. (II-B) 5. Pelvic pain: A multidisciplinary approach is recommended, as there is little evidence that hysterectomy will cure chronic pelvic pain. When the pain is confined to dysmenorrhea or associated with significant pelvic disease, hysterectomy may offer relief. (II-C) Preinvasive Disease 1. Hysterectomy is usually indicated for endometrial hyperplasia with atypia. (I-A) 2. Cervical intraepithelial neoplasia in itself is not an indication for hysterectomy. (I-B) 3. Simple hysterectomy is an option for treatment of adenocarcinoma in situ of the cervix when invasive disease has been excluded. (I-B) Invasive Disease 1. Hysterectomy is an accepted treatment or staging procedure for endometrial carcinoma. It may play a role in the staging or treatment of cervical, epithelial ovarian, and fallopian tube carcinoma. (I-A) Acute Conditions 1. Hysterectomy is indicated for intractable postpartum hemorrhage when conservative therapy has failed to control bleeding. (II-B) 2. Tubo-ovarian abscesses that are ruptured or do not respond to antibiotics may be treated with hysterectomy and bilateral salpingo-oophorectomy in selected cases. (I-C) 3. Hysterectomy may be required for cases of acute menorrhagia refractory to medical or conservative surgical treatment. (II-C) Other Indications 1. Consultation with an oncologist or geneticist is recommended when considering hysterectomy and prophylactic oophorectomy for a familial history of ovarian cancer. (III-C) Surgical Approach 1. The vaginal route shoe should be considered as a first choice for all benign indications. The laparoscopic approach should be considered when it reduces the need for a laparotomy. (III-B) VALIDATION: Medline searches were performed in preparing this guideline with input from experts in their field across Canada. The guideline was reviewed and accepted by SOGC Council and Executive.
The Society of Obstetricians and Gynaecologists of Canada.
确定子宫切除术的适应证、术前评估以及子宫切除术前所需的可用替代方案。患者自我报告的子宫切除术后结果显示患者满意度较高。通过仔细的术前评估和对其他治疗选择的讨论,这些满意度可能会最大化。在大多数情况下,进行子宫切除术是为了缓解症状并改善生活质量。必须仔细考虑患者对治疗替代方案的偏好。
制定本指南时考虑的临床实践领域包括术前评估,包括替代治疗、子宫切除方法的选择以及风险和益处的评估。风险效益比必须由女性及其医疗保健从业者分别进行审查。
在考虑疾病过程、可用的替代治疗和选项,并审查了风险和预期益处之后,优化女性及其护理人员进行子宫切除术的决策过程。
使用Medline、PubMed和Cochrane数据库,对1996年至2001年的英文文章以及1996年SOGC指南中发表的综述进行了审查。证据水平已根据加拿大定期健康检查特别工作组描述的标准确定。
益处、危害和成本:子宫切除术是某些妇科疾病的首选治疗方法。必须仔细权衡手术的预期优势与手术及其他治疗替代方案可能存在的风险。在选择合适的患者中,手术结果应是生活质量的改善。手术对医疗保健系统和患者的成本必须在未治疗疾病的成本背景下进行解读。选择的子宫切除方法将影响手术成本。
良性疾病1. 子宫肌瘤:对于有症状的肌瘤,子宫切除术为月经过多和与子宫增大相关的压迫症状提供了永久性解决方案。(I-A)2. 异常子宫出血:必须排除子宫内膜病变,应首先考虑药物替代治疗。(III-B)3. 子宫内膜异位症:在存在严重症状且其他治疗失败且不再需要生育时,通常需要进行子宫切除术。(I-B)4. 盆腔脏器脱垂:手术解决方案通常包括阴道子宫切除术,但必须包括盆腔支持手术。(II-B)5. 盆腔疼痛:建议采用多学科方法,因为几乎没有证据表明子宫切除术能治愈慢性盆腔疼痛。当疼痛局限于痛经或与严重盆腔疾病相关时,子宫切除术可能会缓解疼痛。(II-C)癌前疾病1. 非典型子宫内膜增生通常需要进行子宫切除术。(I-A)2. 宫颈上皮内瘤变本身不是子宫切除术的指征。(I-B)3. 当排除浸润性疾病时,单纯子宫切除术是治疗宫颈原位腺癌的一种选择。(I-B)浸润性疾病1. 子宫切除术是子宫内膜癌公认的治疗或分期程序。它可能在宫颈癌、上皮性卵巢癌和输卵管癌的分期或治疗中发挥作用。(I-A)急性情况1. 当保守治疗未能控制出血时,子宫切除术适用于难治性产后出血。(II-B)2. 在某些选定病例中,破裂或对抗生素无反应的输卵管卵巢脓肿可通过子宫切除术和双侧输卵管卵巢切除术进行治疗。(I-C)3. 对于药物或保守手术治疗无效的急性月经过多病例,可能需要进行子宫切除术。(II-C)其他指征1. 当考虑因卵巢癌家族史进行子宫切除术和预防性卵巢切除术时,建议咨询肿瘤学家或遗传学家。(III-C)手术方法1. 对于所有良性指征,应首先考虑经阴道途径。当减少剖腹手术的必要性时,应考虑腹腔镜手术方法。(III-B)验证:在编写本指南时进行了Medline检索,并得到了加拿大各地该领域专家的意见。该指南经SOGC理事会和执行委员会审查并接受。
加拿大妇产科学会。