Kukoba T V, Seredenko M M, Butovych I A, Moĭbenko O O
O. O. Bogomoletz Institute of Physiology, Ukrainian National Academy of Sciences.
Fiziol Zh (1994). 1998;44(5-6):43-8.
It was studied the effect of new blocker of lipoxygenase way of arachidontic acid metabolism--linoleyl-hydroxamic acid--on the status of lipid peroxidation and antioxidant system in blood, heart, liver, lung and brain in rats under acute hypoxic hypoxia. It was shows that preliminary introduction of this substance lead to increase of antioxidant enzymes activity--superoxide dismutase and ceruloplasmine, and to decrease of lipid peroxidation level during hypoxia in blood, heart, liver and lung (without brain).
研究了花生四烯酸代谢脂氧合酶途径的新型阻滞剂——亚油基异羟肟酸，对急性低氧性缺氧大鼠血液、心脏、肝脏、肺和脑组织脂质过氧化状态及抗氧化系统的影响。结果表明，预先给予该物质可导致抗氧化酶活性增加——超氧化物歧化酶和铜蓝蛋白活性增加，同时可降低血液、心脏、肝脏和肺（不包括脑）在缺氧期间的脂质过氧化水平。
