A novel metal iodide promoted three-component synthesis of substituted pyrrolidines.
作者信息
Bertozzi Fabio, Gustafsson Magnus, Olsson Roger
机构信息
Discovery Chemistry, ACADIA Pharmaceuticals A/S, Fabriksparken 58, DK-2600 Glostrup, Denmark.
出版信息
Org Lett. 2002 Sep 5;4(18):3147-50. doi: 10.1021/ol0264814.
PMID:12201738
Abstract
[reaction: see text] A new one-pot procedure for the synthesis of substituted pyrrolidine derivatives with commercially available cyclopropyl ketones, aldehydes, and amines by a metal iodide promoted three-component reaction was developed.
摘要
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