Wells Alan, Marti Ulrich
Department of Pathology, 713 Scaife, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.
Nat Rev Mol Cell Biol. 2002 Sep;3(9):697-702. doi: 10.1038/nrm905.
Do cell-surface growth-factor receptors and their ligands accumulate in the nucleoplasm under physiological conditions? And, if so, how do they get there and what function do they serve in this location? Recent advances have provided tantalizing hints to the answers to these questions, and hold the key to identifying a new mode of signal transduction.
在生理条件下，细胞表面生长因子受体及其配体是否会在核质中积累？如果是，它们是如何到达那里的，以及在这个位置发挥什么功能？最近的进展为这些问题的答案提供了诱人的线索，并为识别一种新的信号转导模式提供了关键。
