Minor P D
NIBSC, Potters Bar, Herts, UK.
Dev Biol (Basel). 2002;108:15-9.
Transmission of viruses such as HBV, HIV and HCV by blood components and protein fractions are well documented and precautions based on donor selection and screening as well as processing are well established and effective. Other viruses, including small non-enveloped viruses, pose a greater challenge for removal, but are considered less hazardous clinically. While cell associated viruses such as HTLVI and CMV pose a risk to certain kinds of recipient of blood components the biggest single current issue is that of vCJD following the BSE epidemic in the United Kingdom.
诸如乙肝病毒（HBV）、人类免疫缺陷病毒（HIV）和丙型肝炎病毒（HCV）通过血液成分和蛋白质组分传播已有充分记录，基于献血者选择、筛查以及血液处理的预防措施也已完善且有效。其他病毒，包括小型无包膜病毒，在去除方面面临更大挑战，但在临床上被认为危害较小。虽然诸如人类嗜T淋巴细胞病毒I型（HTLVI）和巨细胞病毒（CMV）等细胞相关病毒对某些血液成分接受者构成风险，但当前最大的单一问题是英国疯牛病疫情之后出现的变异型克雅氏病（vCJD）。
