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一组特纳综合征患者的口腔和临床特征。

Oral and clinical characteristics of a group of patients with Turner syndrome.

作者信息

López María Elena, Bazán Cristina, Lorca Irma Alcira, Chervonagura Amalia

机构信息

Cátedra de Química Biológia, Faculdad de Odontología, Universidad Nacional De Tucumán, Argentinia.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Aug;94(2):196-204. doi: 10.1067/moe.2002.121546.

Abstract

OBJECTIVE

The loss of the X chromosome in girls with Turner syndrome (TS) affects the shape and the size of craniofacial structures. Few studies have been reported on female patients with TS in South America. Records of odontologic alterations of 23 Argentinian patients with TS were compared with those of 25 girls in a control group, and associations were made with medical indications.

STUDY DESIGN

Oral clinical diagnoses were completed with periapical, occlusal, panoramic, and orthopantomograms; urine and blood determinations were performed by conventional methods.

RESULTS

Blood phosphorus and calcium levels were altered, and osteoporosis was detected. In some patients, TS was associated with autoimmune thyroiditis. Control subjects had normal blood and urine values. The decayed, missing, and filled permanent surfaces index for temporary teeth was statistically higher for the control group. About 78% of the patients had hypoplasia, 65% had reduced root length and bifurcated roots, and 100% had high arch palate. Incisor asymmetry was also observed.

CONCLUSIONS

Medical and laboratory indexes are essentially indicative of hormone alterations. TS patients have a particular oral anatomy that could be closely related to an alteration in calcium and phosphorus metabolism.

摘要

目的

特纳综合征(TS)女童的X染色体缺失会影响颅面结构的形状和大小。南美洲关于TS女性患者的研究报道较少。将23例阿根廷TS患者的口腔改变记录与25名对照组女童的记录进行比较,并与医学指征建立关联。

研究设计

通过根尖片、咬合片、全景片和曲面断层片完成口腔临床诊断;采用常规方法进行尿液和血液检测。

结果

血液磷和钙水平发生改变,检测到骨质疏松。部分患者的TS与自身免疫性甲状腺炎有关。对照组的血液和尿液值正常。对照组乳牙的龋失补牙面指数在统计学上更高。约78%的患者有发育不全,65%的患者牙根长度缩短且牙根分叉,100%的患者有高拱腭。还观察到切牙不对称。

结论

医学和实验室指标基本表明存在激素改变。TS患者具有特定的口腔解剖结构,可能与钙磷代谢改变密切相关。

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