Cabrera H, Gómez M L, García S
Department of Dermatology, School of Medicine of Buenos Aires University, Argentina, Hospital Posadas.
J Eur Acad Dermatol Venereol. 2002 Jul;16(4):377-9. doi: 10.1046/j.1468-3083.2002.00569.x.
Giant congenital melanocytic nevi (GCMN) are rare and occur in about one out of every 200,000-500,000 births. Their importance resides in the aesthetic alteration they produce and in the possibility of malignant transformation or in their association with nevi in the central nervous system as a distinctive syndrome: neurocutaneous melanoblastosis or nevomatosis, due to the fact that nervous system lesions are produced by infiltration of nevus cells. We present here a patient with a combination of GCMN with an outstanding lipomatosis located on the same area.
巨大先天性黑素细胞痣（GCMN）很罕见，每20万至50万例出生中约有1例发生。其重要性在于它们所导致的美学改变、恶性转化的可能性，或者在于它们与中枢神经系统痣相关联形成一种独特综合征：神经皮肤黑素母细胞增多症或痣瘤病，这是因为神经系统病变是由痣细胞浸润引起的。我们在此展示一名患有GCMN并在同一区域伴有显著脂肪瘤病的患者。
