Kamiyoshihara Mitsuhiro, Sakata Kazuhiro, Otani Yoshimi, Kawashima Osamu, Takahashi Toru, Morishita Yasuo
Department of Thoracic and Cardiovascular Surgery, Maebashi Red Cross Hospital, 3-21-36 Asahi-Cho, Maebashi, Gunma 371-0014, Japan.
Jpn J Thorac Cardiovasc Surg. 2002 Aug;50(8):343-6. doi: 10.1007/BF03032629.
A 75-year-old woman admitted for an abnormal chest X-ray shadow was found in transbronchial lung biopsy to have malignant cells. After right lower lobectomy with mediastinal lymph node dissection, pathological examination showed primary pulmonary squamous cell carcinoma (pT2N1M0, stage IIB). After discharge, we followed her up as an outpatient, with oral administration of uracil and futrafur (300 mg/day). Five months postoperatively, a subcutaneous mass detected on her back and surgically removed was found histologically to be metastatic squamous cell carcinoma of subcutaneous tissue from lung cancer. No other metastases were found. The patient has survived 3 years and 3 months since primary surgery and remained cancer-free 2 years and 11 months since resection for skin metastasis. Given that skin metastasis is detected when most patients are in an advanced stage of disease, our case was a rare one of solitary skin metastasis after resection for lung cancer.
一名因胸部X线阴影异常入院的75岁女性,经支气管肺活检发现有恶性细胞。在进行右下叶切除及纵隔淋巴结清扫术后,病理检查显示为原发性肺鳞状细胞癌(pT2N1M0,IIB期)。出院后,我们对她进行门诊随访,口服尿嘧啶和替加氟(300毫克/天)。术后五个月,在她背部检测到一个皮下肿块并手术切除,组织学检查发现是肺癌皮下组织转移性鳞状细胞癌。未发现其他转移灶。自初次手术以来,患者已存活3年3个月,自皮肤转移灶切除以来,已无癌生存2年11个月。鉴于大多数患者在疾病晚期才检测到皮肤转移,我们的病例是肺癌切除术后罕见的孤立性皮肤转移病例。