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微创经皮后路腰椎椎间融合术

Minimally invasive percutaneous posterior lumbar interbody fusion.

作者信息

Khoo Larry T, Palmer Sylvain, Laich Daniel T, Fessler Richard G

机构信息

Institute for Spine Care, Chicago Institute of Neurosurgery and Neuroresearch, Rush Presbyterian Medical Center, Chicago, Illinois, USA.

出版信息

Neurosurgery. 2002 Nov;51(5 Suppl):S166-81.

Abstract

OBJECTIVE

The wide exposure required for a standard posterior lumbar interbody fusion (PLIF) can cause unnecessary trauma to the lumbar musculoligamentous complex. By combining existing microendoscopic, percutaneous instrumentation and interbody technologies, a novel, minimally invasive, percutaneous PLIF technique was developed to minimize such iatrogenic tissue injury (MIP-PLIF).

METHODS

The MIP-PLIF technique was validated in three cadaveric torsos with six motion segments decompressed and fused. Preoperative variables measured from imaging included interpedicular distance, pedicular height and width, interspinous distance, lordosis, intervertebral height, Cobb angle, and foraminal height and volume. Using the METRx and MD spinal access systems (Medtronic Sofamor Danek, Memphis, TN), bilateral laminotomies were performed using a hybrid of microsurgical and microendoscopic techniques. The intervertebral disc spaces were then distracted and prepared with the Tangent (Medtronic Sofamor Danek) interbody instruments. Either a 10 or 12 by 22 mm interbody graft was then placed. Using the Sextant (Medtronic Sofamor Danek) system, percutaneous pedicle screw-rod fixation of the motion segment was completed. We then applied MIP-PLIF in three patients.

RESULTS

For segments with preoperative intervertebral/foraminal height loss, MIP-PLIF was effective in restoring both heights in all cases. The amount of improvement (9.7 to 38% disc height increase; 7.7 to 29.9% foraminal height increase) varied directly with the size of the graft used and the original degree of disc and foraminal height loss. Segmental lordosis improved by 29% on average. Graft and screw placement was accurate in the cadavers, except for a single Grade 1 screw violation of one pedicle. The average operative time was 3.5 hours per level. In our three clinical cases, the MIP-PLIF procedure required a mean of 5.4 hours, estimated blood loss was 185 ml, and inpatient stay was 2.8 days, with no intravenous narcotic use after 2 days in any of the patients. All screw and graft placements were confirmed.

CONCLUSION

A complete PLIF procedure can be safely and effectively performed using minimally invasive techniques, thereby potentially reducing the pain and morbidity associated with standard open surgery. Prospective, randomized outcome studies will be required to validate the efficacy of this exciting new surgical technique.

摘要

目的

标准后路腰椎椎间融合术(PLIF)所需的广泛暴露可能会对腰椎肌肉韧带复合体造成不必要的创伤。通过结合现有的显微内镜、经皮器械和椎间技术,开发了一种新型的、微创的经皮PLIF技术(MIP-PLIF),以尽量减少此类医源性组织损伤。

方法

在三个尸体躯干上对MIP-PLIF技术进行验证,对六个运动节段进行减压和融合。术前从影像学测量的变量包括椎弓根间距、椎弓根高度和宽度、棘突间距离、腰椎前凸、椎间高度、Cobb角以及椎间孔高度和容积。使用METRx和MD脊柱通路系统(美敦力索法玛丹尼克公司,田纳西州孟菲斯),采用显微外科和显微内镜技术相结合的方法进行双侧椎板切开术。然后使用Tangent椎间器械撑开并准备椎间隙。随后置入10×22mm或12×22mm的椎间融合器。使用Sextant系统(美敦力索法玛丹尼克公司)完成运动节段的经皮椎弓根螺钉-棒固定。然后我们在三名患者中应用了MIP-PLIF。

结果

对于术前椎间/椎间孔高度丢失的节段,MIP-PLIF在所有病例中均能有效恢复两者的高度。改善程度(椎间盘高度增加9.7%至38%;椎间孔高度增加7.7%至29.9%)与所用融合器的大小以及椎间盘和椎间孔高度丢失的原始程度直接相关。节段性腰椎前凸平均改善29%。在尸体中,融合器和螺钉放置准确,除了一个椎弓根有一例1级螺钉穿破。平均手术时间为每节段3.5小时。在我们的三个临床病例中,MIP-PLIF手术平均需要5.4小时,估计失血量为185ml,住院时间为2.8天,所有患者术后2天均未使用静脉麻醉剂。所有螺钉和融合器放置均得到确认。

结论

使用微创技术可以安全有效地完成完整的PLIF手术,从而有可能减轻与标准开放手术相关的疼痛和发病率。需要进行前瞻性、随机对照研究来验证这种令人兴奋的新手术技术的疗效。

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