Jiang Chao, Yin Si, Wei Jianmin, Zhao Weigong, Wang Xiaohui, Zhang Yongyuan, Hao Dingjun, Du Heng
Department of Orthopaedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.
J Pain Res. 2021 Dec 14;14:3815-3826. doi: 10.2147/JPR.S338027. eCollection 2021.
The purpose of this study was to introduce and evaluate the early clinical outcomes of the full-endoscopic posterior lumbar interbody fusion (Endo-PLIF) technique with epidural anesthesia (EA) for single-segment lumbar degenerative diseases.
In this retrospective case series study, we explored the feasibility and effectiveness of the Endo-PLIF with EA for single-segment lumbar degenerative diseases. Between March 2018 and January 2019, a series of 24 patients with single-segment lumbar degenerative diseases underwent Endo-PLIF surgery and were followed up for a minimum of 12 months (15.21±2.27 months). Clinical outcomes including visual analog scale (VAS) scores for back and leg pain, Oswestry Disability Index (ODI) scores, and the Short Form-36 health survey questionnaire (SF-36) were evaluated preoperatively, and postoperatively at 3 days and at 3, 6, and 12-months.
All patients underwent successful single-segment Endo-PLIF surgery. The mean operation time was 209.17±39.49 min, and average amount of bleeding was 43.33±14.87 mL. The VAS for lower extremity pain and back pain significantly improved at 3 days, and at 3, 6, 12 months compared with preoperative, respectively. The ODI scores decreased from 42.04±3.96 to 12.75±2.71 (<0.001) at preoperative and 12 months postoperatively, respectively. The SF-36 Physical Component Scores (PCS) improved from 34.96±4.63 preoperatively to 52.08±6.05 (<0.001) at 12 months postoperatively. Additionally, the SF-36 Mental Component Scores (MCS) improved from 39.38±5.70 at preoperative to 53.13±5.97 (<0.001) at 12 months postoperatively. Two patients experienced dysesthesia, and one patient had a wound infection.
Endo-PLIF with EA is a feasible and valuable technique for the treatment of single-segment lumbar degenerative diseases in selected patients.
本研究旨在介绍和评估采用硬膜外麻醉(EA)的全内镜下腰椎后路椎间融合术(Endo-PLIF)治疗单节段腰椎退行性疾病的早期临床疗效。
在这项回顾性病例系列研究中,我们探讨了Endo-PLIF联合EA治疗单节段腰椎退行性疾病的可行性和有效性。2018年3月至2019年1月期间,对一系列24名单节段腰椎退行性疾病患者进行了Endo-PLIF手术,并进行了至少12个月(15.21±2.27个月)的随访。术前、术后3天以及术后3、6和12个月评估临床疗效,包括背部和腿部疼痛的视觉模拟量表(VAS)评分、Oswestry功能障碍指数(ODI)评分以及简明健康调查量表(SF-36)。
所有患者均成功接受了单节段Endo-PLIF手术。平均手术时间为209.17±39.49分钟,平均出血量为43.33±14.87毫升。与术前相比,下肢疼痛和背部疼痛的VAS评分在术后3天以及术后3、6、12个月时均显著改善。术前和术后12个月时,ODI评分分别从42.04±3.96降至12.75±2.71(<0.001)。术后12个月时,SF-36身体成分评分(PCS)从术前的34.96±4.63提高至52.08±6.05(<0.001)。此外,术后12个月时,SF-36精神成分评分(MCS)从术前的39.38±5.70提高至53.13±5.97(<0.001)。2例患者出现感觉异常,1例患者发生伤口感染。
对于部分选择的患者,Endo-PLIF联合EA是一种治疗单节段腰椎退行性疾病可行且有价值的技术。