Redwan El-Rashdy M, Al-Awady Mostafa K
Protein Research Department, GEBRI, Mubarak City for Scientific Research and Biotechnology Application, New Borg El-Arab, Alexandria, Egypt.
Hum Antibodies. 2002;11(1-2):55-9.
Our aim was to determine the level of tetanus immunity in the general Egyptian population. The surveyed population consisted of 709 healthy subjects from five regions of Egypt, 2 month to 105 years of age. We used an ELISA assay to determine titers of anti-tetanus IgG. According to the widely used criteria, 31.7% was susceptible to tetanus (IgG level < 0.15 IU/ml), 15.7% protection (0.15-1.0 IU/ml), and 52.6% > or = 1.0 IU/ml). The results revealed that the majority (68.3%) population from 2 months to 50 years had a protective level of IgG against tetanus. The level of susceptibility increases with age until it reaches 90.3% Significantly, more males (23.7%) unprotected against tetanus. Our results suggest that monitoring immunization status and administering the tetanus vaccine as required are essential to insure adequate and long-lasting antibody levels.
我们的目的是确定埃及普通人群的破伤风免疫水平。被调查人群包括来自埃及五个地区的709名健康受试者，年龄在2个月至105岁之间。我们使用酶联免疫吸附测定法来测定抗破伤风IgG的滴度。根据广泛使用的标准，31.7%的人对破伤风易感（IgG水平<0.15 IU/ml），15.7%的人有保护作用（0.15 - 1.0 IU/ml），52.6%的人IgG水平≥1.0 IU/ml。结果显示，2个月至50岁的大多数人群（68.3%）对破伤风具有保护性IgG水平。易感性水平随年龄增长而增加，直至达到90.3%。值得注意的是，未受破伤风保护的男性比例更高（23.7%）。我们的结果表明，监测免疫状况并根据需要接种破伤风疫苗对于确保足够且持久的抗体水平至关重要。
