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澳大利亚高中生人群中沙眼衣原体的检测

Detection of Chlamydia trachomatis in an Australian high school student population.

作者信息

Debattista J, Martin P, Jamieson J, Crane K, Dolton I, Russell-Hall S, DeSilva J, Hargrave R, Robinson T, Ryan N, Mortlock M

机构信息

Centre for Molecular Biology, Qld University of Technology/Sexual Health and AIDS Service, The Prince Charles Hospital Health Service District, Brisbane, Australia.

出版信息

Sex Transm Infect. 2002 Jun;78(3):194-7. doi: 10.1136/sti.78.3.194.

Abstract

OBJECTIVE

To assess the prevalence of Chlamydia trachomatis infections among an Australian high school adolescent population.

METHODS

Over a 4 year period, 14 high schools were selected in which an infertility prevention programme targeting C. trachomatis was delivered to senior student populations. Coded first catch urine specimens were analysed by Amplicor PCR and infected students treated. Data retrospectively obtained from chlamydia screening programmes conducted among disadvantaged young people detached from formal education were also collated for comparison.

RESULTS

Of a total student test population of 1174, 15 (1.3%; 95% CI 0.7% to 2.1%) were diagnosed with C. trachomatis. Of 516 females and 658 males, 12 (2.3%; 95% CI 1.1% to 4.1%) and 3 (0.5%; 95% CI 0.1% to 1.4%) were tested positive respectively. Data collated for three populations of disadvantaged youth returned at total of 89 C. trachomatis infections out of 560 people (15.9% 95%CI 13.0-19.2%).

CONCLUSION

The overall prevalence of C. trachomatis infection among this population of senior high school adolescents is low, and significantly differs from the higher chlamydia rates detected in disadvantaged adolescents detached from formal schooling (p<0.0001).

摘要

目的

评估澳大利亚高中青少年人群中沙眼衣原体感染的患病率。

方法

在4年时间里,选取了14所高中,针对高年级学生群体开展了一项针对沙眼衣原体的不孕症预防计划。对编码的首次晨尿标本进行Amplicor PCR分析,并对感染学生进行治疗。还整理了从脱离正规教育的弱势青年中开展的衣原体筛查项目中回顾性获得的数据进行比较。

结果

在总共1174名学生检测人群中,15人(1.3%;95%可信区间0.7%至2.1%)被诊断为沙眼衣原体感染。在516名女性和658名男性中,分别有12人(2.3%;95%可信区间1.1%至4.1%)和3人(0.5%;95%可信区间0.1%至1.4%)检测呈阳性。整理的三类弱势青年人群的数据显示,560人中共有89人感染沙眼衣原体(15.9%,95%可信区间13.0 - 19.2%)。

结论

该高中青少年人群中沙眼衣原体感染的总体患病率较低,与脱离正规学校教育的弱势青少年中检测到的较高衣原体感染率有显著差异(p<0.0001)。

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