Suppr超能文献

[儿童几种类型大动脉转位(TGA)的发病率及自然病史(作者译)]

[Frequency and natural history of several types of transpositions of the great arteries (TGA) in children (author's transl)].

作者信息

Popczyńska-Markowa M, Jawień A, Januś S

出版信息

Probl Med Wieku Rozwoj. 1975;5:221-6.

PMID:1223873
Abstract

The frequency and clinical differences between several types of TGA have been estimated. In a group of 52 patients with TGA three anatomic types were distinguished on the basis of the classification of Nadas (Fig. 1). The correlation between TGA type and sex, weight at birth, predominating clinical symptoms, most frequent clinical complications and survival time in children with this congenital malformation were investigated (Fig. 1-6). Type I was found almost five times more frequently in boys who had a higher than average weight at birth (Fig. 1-3). The most frequent clinical symtpoms were: cyanosis, early congestive heart failure and paroxysmal anoxemia (Fig. 4). Infants with this TGA type died much earlier than infants with other TGA types (Fig. 6). The frequency of type IIA was the lowest, similar in both sexes (Fig. 1). Among clinical symptoms cyanosis, paroxysmal anoxemia and systolic murmurs prevailed. No congestive heart failure was observed in this type (Fig. 4). Type IIC was more frequent in boys, but simultaneously it was the most frequent TGA type noticed in female infants (Fig. 1). Almost in all children heart murmurs were found, but only one of the examined cases with this type was affected by congestive heart failure (Fig. 4). The above-mentioned differences between clinical symptoms of several types of transposition of great arteries can be helpful when the adequate treatment is chosen.

摘要

已经估算了几种类型的大动脉转位(TGA)之间的发生率及临床差异。在一组52例大动脉转位患者中,根据纳达斯分类法区分出三种解剖类型(图1)。研究了大动脉转位类型与性别、出生体重、主要临床症状、最常见临床并发症以及患有这种先天性畸形儿童的生存时间之间的相关性(图1 - 6)。I型在出生体重高于平均水平的男孩中出现的频率几乎是其他情况的五倍(图1 - 3)。最常见的临床症状为:发绀、早期充血性心力衰竭和阵发性缺氧血症(图4)。患有这种大动脉转位类型的婴儿比患有其他类型大动脉转位的婴儿死亡要早得多(图6)。IIA型的发生率最低,在两性中相似(图1)。临床症状中,发绀、阵发性缺氧血症和收缩期杂音较为常见。该类型未观察到充血性心力衰竭(图4)。IIC型在男孩中更常见,但同时也是在女婴中发现的最常见的大动脉转位类型(图1)。几乎所有患儿都发现有心脏杂音,但该类型中只有一例受检病例出现充血性心力衰竭(图4)。在选择适当治疗方法时,上述几种类型大动脉转位临床症状之间的差异可能会有所帮助。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验