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[单侧肾病所致高血压中分离肾素的诊断和预后价值]

[Diagnostic and prognostic value of the separated renin in hypertension due to monolateral nephropathy].

作者信息

Pessina A C, Corgnati A, Dal Palù C

出版信息

Quad Sclavo Diagn. 1975 Jun;11(2):257-65.

PMID:1223937
Abstract

Renin activity in renal vein plasma and in peripheral plasma was measured in twentytwo hypertensive patients presenting unilateral renal artery stenosis or other unilateral renal abnormalities. A discrepancy between peripheral and renal vein renin levels was noted only in one case. In seven patients the difference between the renal vein renin of the diseased kidney and that of its contralateral mate was very significant. They responded successfully to surgery for hypertension, confirming the predictive value of a renal vein renin ratio greater than 1.5. In all the other patients with less significant differences between the renin levels of the two kidneys surgery was not performed because they benefited from the hypotensive therapy.

摘要

对22例患有单侧肾动脉狭窄或其他单侧肾脏异常的高血压患者,测定了肾静脉血浆和外周血浆中的肾素活性。仅在1例患者中发现外周和肾静脉肾素水平存在差异。7例患者患侧肾脏与对侧肾脏的肾静脉肾素差异非常显著。他们接受高血压手术后效果良好,证实了肾静脉肾素比值大于1.5的预测价值。在所有其他两侧肾脏肾素水平差异不显著的患者中,未进行手术,因为他们从降压治疗中获益。

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