一种使用氮检测器测定丙咪嗪和去甲丙咪嗪的灵敏气相色谱法。
A sensitive GLC method for the determination of imipramine and desmethylimipramine using a nitrogen detector.
作者信息
Cooper T B, Allen D, Simpson G M
出版信息
Psychopharmacol Commun. 1975;1(4):445-54.
PMID:1224013
Abstract
A sensitive method for determination of imipramine and desmethylimipramine using a GLC system fitted with a new nitrogen detector is described. The lower limit of sensitivity is less than 1 ng/ml with a lower limit enabling quantitation with acceptable precision of 3-5 ng/ml. Data from 20 control subjects given a single oral dose of imipramine are shown.
摘要
描述了一种使用配备新型氮检测器的气相色谱系统测定丙咪嗪和去甲丙咪嗪的灵敏方法。灵敏度下限低于1纳克/毫升，下限使得能够以3 - 5纳克/毫升的可接受精密度进行定量。给出了20名单次口服丙咪嗪的对照受试者的数据。
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