Singh Digvijay, Singh Ajay
National Bureau of Fish Genetic Resources, Lucknow, UP, India.
Chemosphere. 2002 Oct;49(1):45-9. doi: 10.1016/s0045-6535(02)00178-9.
Mortality caused by the aqueous extracts of leaf and stem bark of four plants belonging to family Euphorbiaceae and Apocynaceae against freshwater fish Channa punctatus has been reported. It was found that dilute aqueous solutions of leaf and stem bark were active in killing the fishes. The toxic effect of stem bark of all the plants were time as well as dose dependent. There was significant negative correlation between LC50 and exposure periods. Thus, the LC50 values of stem bark extracts of Euphorbia royleana, Jatropha gossypifolia, Nerium indicum and Thevelia peruviana were decreased from 0.050 g/l (24 h) > to 0.020 g/l (96 h); 4.61 g/l (24 h) > to 4.34 g/l (96 h); 0.097 g/l (24 h) > to 0.041 g/l (96 h) and 4.05 g/l (24 h) > to 3.17 g/l (96 h), respectively. It has been suggested that these plant products cannot be used directly in freshwater bodies, without their detailed studies on long-term effects on non-target organism as well their structure activity relationship.
据报道,大戟科和夹竹桃科四种植物的叶和茎皮水提取物对淡水鱼斑鳢具有致死性。研究发现,叶和茎皮的稀水溶液对鱼类具有致死活性。所有植物茎皮的毒性作用均具有时间和剂量依赖性。半数致死浓度(LC50)与暴露时间之间存在显著的负相关。因此,大戟、棉叶麻风树、夹竹桃和黄花夹竹桃茎皮提取物的LC50值分别从0.050克/升(24小时)降至0.020克/升(96小时);从4.61克/升(24小时)降至4.34克/升(96小时);从0.097克/升(24小时)降至0.041克/升(96小时);从4.05克/升(24小时)降至3.17克/升(96小时)。有人建议,在未对这些植物产品对非目标生物的长期影响及其构效关系进行详细研究之前,不能直接将其用于淡水水体。