National Bureau of Fish Genetic Resources, Canal Ring Road, P.O. Dilkusha, Lucknow 226 002, UP, India; Department of Zoology, D.D.U. Gorakhpur University, Gorakhpur 273 009, UP, India.
Environ Toxicol Pharmacol. 2002 Oct;12(3):129-36. doi: 10.1016/s1382-6689(02)00016-9.
Exposure of fish over 96 h to 40 and 80% of LC(50) (24 h) of aqueous latex extracts of Euphorbia royleana and Jatropha gossypifolia of family Euphorbiaceae significantly altered the level of total protein, total free amino acids, nucleic acids, pyruvate, lactate, glycogen and as well as protease activity also in muscle, liver and gonadal tissue of the fish Channa punctatus. The alterations in all the biochemical parameters were significantly dose-dependent. Withdrawal study also shows that there is a partial recovery in the levels of glycogen, pyruvate, lactate and nucleic acids, but nearly complete recovery in total protein, total free amino acids level and protease activity in all the three tissues of the fish after the 7th day of the withdrawal of treatment, which supports the view that the plant product is safer in use as pesticides for control of common weed fishes in culture ponds.
暴露于 40%和 80%的大戟科Euphorbia royleana 和 Jatropha gossypifolia 水乳胶提取物中超过 96 小时后，鱼类的总蛋白、总游离氨基酸、核酸、丙酮酸、乳酸、糖原以及肌肉、肝脏和性腺组织中的蛋白酶活性显著改变。所有生化参数的变化均呈显著的剂量依赖性。撤出研究还表明，在撤出处理后的第 7 天，鱼类所有三种组织中的糖原、丙酮酸、乳酸和核酸水平部分恢复，但总蛋白、总游离氨基酸水平和蛋白酶活性几乎完全恢复，这支持了植物产品作为控制养殖池塘中常见杂草鱼类的农药更安全的观点。
