慢性皮肤癣菌病中对上皮组织具有亲和力的抗体。

Antibodies with affinity for epithelial tissue in chronic dermatophytosis.

作者信息

Hopfer R L, Grappel S F, Blank F

出版信息

Dermatologica. 1975;151(3):135-43. doi: 10.1159/000251326.

Abstract

Antibodies to dermatophytes which also had affinity for intercellular material of epithelial tissue, were detected in sera from 80% of patients with chronic dermatophytosis using an indirect fluorescent antibody test. The class of immunoglobulins reactive with both the dermatophyte and the epithelial tissue was identified as IgM. IgM antibodies with affinity for arthrospores of Trichophyton mentagrophytes and intercellular substance of epithelial tissue could be removed from sera with mycelium of Trichophyton rubrum.

摘要

使用间接荧光抗体试验，在80%的慢性皮肤癣菌病患者血清中检测到了对皮肤癣菌的抗体，这些抗体对上皮组织的细胞间物质也具有亲和力。与皮肤癣菌和上皮组织均发生反应的免疫球蛋白类别被鉴定为IgM。对须癣毛癣菌的关节孢子和上皮组织细胞间物质具有亲和力的IgM抗体，可以用红色毛癣菌的菌丝体从血清中去除。