Bachmayer H
Intervirology. 1975;5(5):260-72. doi: 10.1159/000149923.
A novel approach is described for the isolation of hemagglutinin and neuraminidase from influenza viruses. In contrast to published procedures, the two glycoproteins are selectively solubilized, leaving an intact viral subparticle which contains lipid, RNA and non-glycoproteins. The pronounced differences in size allow a simple separation of the solubilized proteins from the virus 'core'.
本文描述了一种从流感病毒中分离血凝素和神经氨酸酶的新方法。与已发表的方法不同，这两种糖蛋白被选择性地溶解，留下一个完整的病毒亚颗粒，其中包含脂质、RNA和非糖蛋白。由于大小上的显著差异，可以将溶解的蛋白质与病毒“核心”简单分离。
