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用不同去污剂从正常大鼠肝脏和再生大鼠肝脏制备的多核糖体的多肽合成活性比较。

Comparison of the activities for polypeptide synthesis of polysomes prepared with different detergents from normal and regenerating rat liver.

作者信息

Tominaga T, Kitamura M, Azuma Y, Taguchi T, Takeda Y

出版信息

J Biochem. 1975 Jun;77(6):1255-9.

PMID:1225906
Abstract

When prepared in the presence of deoxycholate, the activities for polypeptide synthesis of polysomes from normal and regenerating rat liver were similar. However, when the polysomes were prepared in the presence of either Triton X-100 or Lubrol WX, the polysomes from regenerating liver had about three to four times more activity than those from normal liver. On the other hand, the activities for polyphenylalanine synthesis of ribosomes from regenerating rat liver were similar irrespective of whether these ribosomes were prepared in the presence of deoxycholate or Triton X-100.

摘要

当在脱氧胆酸盐存在的情况下制备时,正常大鼠肝脏和再生大鼠肝脏的多核糖体的多肽合成活性相似。然而,当在Triton X-100或Lubrol WX存在的情况下制备多核糖体时,再生肝脏的多核糖体活性比正常肝脏的多核糖体活性高约三到四倍。另一方面,无论这些核糖体是在脱氧胆酸盐还是Triton X-100存在的情况下制备的,再生大鼠肝脏核糖体的聚苯丙氨酸合成活性都相似。

相似文献

1
Comparison of the activities for polypeptide synthesis of polysomes prepared with different detergents from normal and regenerating rat liver.用不同去污剂从正常大鼠肝脏和再生大鼠肝脏制备的多核糖体的多肽合成活性比较。
J Biochem. 1975 Jun;77(6):1255-9.
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Effects of 6-thioguanine on RNA biosynthesis in regenerating rat liver.
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A procedure for the quantitative recovery of homogeneous populations of undegraded free and bound polysomes from rat liver.一种从大鼠肝脏中定量回收未降解的游离和结合多核糖体均一群体的方法。
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The effect of phenobarbital on the synthesis of nascent protein on free and membrane-bound polyribosomes of normal and regenerating liver.苯巴比妥对正常及再生肝脏游离和膜结合多核糖体上新合成蛋白质合成的影响。
Mol Pharmacol. 1972 Nov;8(6):701-10.
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Protein synthesis by microsomal particles from regenerating rat liver.来自再生大鼠肝脏的微粒体颗粒的蛋白质合成
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[Kinetics of the in vivo synthesis of the polypeptide chain; the effect of translation inhibitors].[多肽链体内合成的动力学;翻译抑制剂的作用]
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引用本文的文献

1
Regeneration of renal proximal tubules after mercuric chloride injury is accompanied by increased binding of aminoacyl-transfer ribonucleic acid.氯化汞损伤后肾近端小管的再生伴随着氨酰转移核糖核酸结合增加。
Biochem J. 1976 Nov 15;160(2):357-65. doi: 10.1042/bj1600357.
2
Studies of a factor from dystrophic mouse muscle inhibitory towards protein synthesis.对来自营养不良小鼠肌肉的一种抑制蛋白质合成的因子的研究。
Biochem J. 1978 Dec 15;176(3):907-17. doi: 10.1042/bj1760907.
3
Growth of liver accompanied by an increased binding of aminoacyl-transfer ribonucleic acids.
肝脏的生长伴随着氨酰转移核糖核酸结合的增加。
Biochem J. 1977 Sep 15;166(3):463-71. doi: 10.1042/bj1660463.