Perry E, Chaudhary R K, Cleary T E, Roughley F R
Can Med Assoc J. 1975 Jan 11;112(1):46-8.
The prevalence of hepatitis B surface antigen (HBsAg) in 155 patients with Down's syndrome (DS) and 209 with other types of mental retardation (OMR) at Huronia Regional Centre, Orillia, Ontario was 34.8 and 5.3%, respectively. There was no significant difference in prevalence between males and females in either group of patients. In 75 matched pairs (DS-OMR) the HBsAg prevalence was 45% in DS and 8.3% in OMR males; in females 40% of those with DS were HBsAg-positive, whereas all the OMR residents were negative. The prevalence of HBsAg in both DS and OMR groups was higher in those admitted in early childhood and in those who had resided in the institution for more than 10 years. In all 54 HBsAg-positive DS patients the antigen subtype was ad. Among the 11 HBsAg-positive OMR patients the subtype was ad in 10 cases and ay in 1.
安大略省奥里利亚市胡罗尼亚地区中心的155名唐氏综合征（DS）患者和209名其他类型智力障碍（OMR）患者中，乙肝表面抗原（HBsAg）的流行率分别为34.8%和5.3%。两组患者中，男性和女性的流行率均无显著差异。在75对匹配组（DS - OMR）中，DS男性的HBsAg流行率为45%，OMR男性为8.3%；女性中，40%的DS患者HBsAg呈阳性，而所有OMR患者均为阴性。DS组和OMR组中，幼儿期入院者以及在该机构居住超过10年者的HBsAg流行率更高。在所有54例HBsAg阳性的DS患者中，抗原亚型均为ad。在11例HBsAg阳性的OMR患者中，10例亚型为ad，1例为ay。
