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三种检测澳大利亚抗原商业制剂的比较研究

[Comparative study of three commerical preparations for the detection of Australia antigen].

作者信息

Le Petit J C, Marcelin M, Berger A, Croze M, Brizard C P

出版信息

Rev Fr Transfus Immunohematol. 1975 Jun;18(2):211-6. doi: 10.1016/s0338-4535(75)80020-1.

Abstract

2,944 sera from blood donors (420 of them being new donors) were tested in four techniques: Counterelectrophoresis (CEP) and three commercial tests: Ausria II, Auscell and Hepanosticon. Over 10 HBs Ag detected by RIA, 8 were evidenced by the Auscell test and 6 by the Hepanosticon Test. False positive results (approximately 3%) represent a disadvantage to the reverse hemagglutination method; this rate increased considerably in a group of 386 patients sera also tested. The authors conclude that the results obtained with the reverse hemagglutination technique are nearing those of RIA.

摘要

对2944份献血者血清(其中420份为首次献血者)采用四种技术进行检测:对流电泳(CEP)以及三种商业检测方法:Ausria II、Auscell和Hepanosticon。通过放射免疫分析检测出10份以上乙肝表面抗原,Auscell检测证实8份,Hepanosticon检测证实6份。反向血凝法存在假阳性结果(约3%)这一缺点;在一组同样接受检测的386份患者血清中,这一比率显著上升。作者得出结论,反向血凝技术所获结果接近放射免疫分析的结果。

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