Broder Samuel, Caplan Arthur, Evans William E
Celera Genomics, Rockville, MD, USA.
J Am Pharm Assoc (Wash). 2002 Sep-Oct;42(5 Suppl 1):S22-3.
The sequence of many genes has been conserved during evolution, offering insights into gene function and new opportunities for research in pharmacology and drug development. The many ethical issues surrounding genetics have the potent tial to halt the genomic revolution unless society strives to understand and resolve these issues. Advances in pharmacogenomics hold significant promise for improved health care, such as by enabling clinicians to select the optimal medications and dosages for individual patients.
许多基因的序列在进化过程中得以保留,这为深入了解基因功能以及药理学和药物开发研究带来了新机遇。围绕遗传学的诸多伦理问题有可能阻碍基因组革命,除非社会努力去理解并解决这些问题。药物基因组学的进展为改善医疗保健带来了巨大希望,例如能让临床医生为个体患者选择最佳药物和剂量。