Pasquis P
Bull Physiopathol Respir (Nancy). 1975 Nov-Dec;11(6):823-36.
The functional residual capacity (FRC) was measured in 24 healthy subjects, 1-by the helium dilution method using a closed system and an open system during washout, and 2-using a constant pressure plethysmograph. Results obtained with the three methods were not significantly different. Furthermore, FRC was determined by helium dilution in 177 healthy men and in 100 healthy women, aged between 18 and 77 years. In both sexes, FRC was dependent on age, height (H) and weight, being greater in the taller, older subjects. For a given height and age, FRC decreased with increasing weight. Correlation coefficients between logarithm of (FRC/H3) and age and/or weight were highly significant. From these allometric relationships, it was possible to calculate FRC reference values, and then, reference values for other functional tests such as steady state TLCO and lung compliance.
对24名健康受试者的功能残气量(FRC)进行了测量,1. 通过在冲洗过程中使用封闭系统和开放系统的氦稀释法,以及2. 使用恒压体积描记器。三种方法获得的结果无显著差异。此外,对177名年龄在18至77岁之间的健康男性和100名健康女性进行了氦稀释法测定FRC。在两性中,FRC均取决于年龄、身高(H)和体重,身高较高、年龄较大的受试者的FRC更大。对于给定的身高和年龄,FRC随体重增加而降低。(FRC/H3)的对数与年龄和/或体重之间的相关系数非常显著。根据这些异速生长关系,可以计算FRC参考值,进而计算其他功能测试(如稳态一氧化碳弥散量(TLCO)和肺顺应性)的参考值。