多形核白细胞和巨噬细胞对淋巴细胞及成纤维细胞体外生长的影响。
The influence of polymorphonuclear leukocytes and macrophages on the growth of lymphocytes and fibroblasts in vitro.
作者信息
Tchórzewski H, Denys A, Lipiński S
出版信息
Exp Pathol (Jena). 1975;10(5-6):289-93. doi: 10.1016/s0014-4908(75)80036-6.
PMID:1233290
Abstract
The influence of polymorphonuclear leukocytes (PMNL) and macrophage plasma, nuclei and lysosome extracts have been tested on lymphocytes and fibroblasts growth in vitro. The stimulatory activity of PMNL lysosomes has been shown on lymphocyte and fibroblast growth. The macrophage lysosomes have shown a similar but lower activity. The role of lysosomes has been suggested in reparation and wound healing processes, presumably in inflammatory cell infiltrated regions.
摘要
已对多形核白细胞（PMNL）以及巨噬细胞的血浆、细胞核和溶酶体提取物对淋巴细胞和成纤维细胞体外生长的影响进行了测试。结果显示，PMNL溶酶体对淋巴细胞和成纤维细胞的生长具有刺激活性。巨噬细胞溶酶体表现出类似但较低的活性。溶酶体在修复和伤口愈合过程中，可能在炎症细胞浸润区域发挥作用。
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