Mills O H, Klingman A M
Arch Dermatol. 1975 Jan;111(1):65-8.
Popular brands of soaps and shampoos were assayed for comedogenicity in the rabbit ear. Only a small number produced hyperkeratosis when applied at a 25% concentration. Bacteriostatic substances, especially hexachlorophene, were mildly comedogenic. Conventional soaps include salts of fatty acids; the latter are known comedogens. The obsessive use of soaps by patients with acne vulgaris may aggravate the disease and result in its extension to unusual locations.
对香皂和洗发水的知名品牌进行了兔耳致粉刺性测定。只有少数产品在以25%的浓度使用时会产生角化过度。抑菌物质，尤其是六氯酚，有轻度致粉刺性。传统肥皂包含脂肪酸盐；后者是已知的致粉刺物。寻常痤疮患者过度使用肥皂可能会加重病情，并导致其扩散到不常见的部位。
