Tamemoto Kimiko, Takaishi Yoshihisa, Kawazoe Kazuyoshi, Honda Gisho, Ito Michiho, Kiuchi Fumiyuki, Takeda Yoshio, Kodzhimatov Olimjon K, Ashurmetov Ozodbek, Shimizu Katsuhide, Nagasawa Hideko, Uto Yoshihiro, Hori Hitoshi
Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Japan.
J Nat Prod. 2002 Sep;65(9):1323-4. doi: 10.1021/np020020+.
An unusual new sesquiterpene derivative, kuhistaferone (1), was isolated from the fruits of the Uzbekistan medicinal plant Ferula kuhistanica. The structure of 1 was established on the basis of spectroscopic evidence. Compound 1 showed moderate cytotoxicity against the human colon tumor cell line HCT116.
从乌兹别克斯坦药用植物库氏阿魏（Ferula kuhistanica）的果实中分离出一种不同寻常的新型倍半萜衍生物——库氏阿魏酮（1）。1的结构是根据光谱证据确定的。化合物1对人结肠肿瘤细胞系HCT116显示出中等程度的细胞毒性。
