Troxel Scott A, Low Roger K
Department of Urology, University of California at Davis, Sacramento, USA.
J Urol. 2002 Oct;168(4 Pt 1):1348-51. doi: 10.1016/S0022-5347(05)64446-1.
Systemic absorption of irrigation fluid containing bacteria or endotoxin may lead to fever and urosepsis after percutaneous nephrolithotomy. Although to our knowledge the exact method of absorption is undefined, intrapelvic pressure greater than 30 mm. Hg has been shown to result in pyelovenous-lymphatic backflow. We measured intrapelvic pressure during percutaneous nephrolithotomy and correlated pressure with postoperative fever and operative technique.
Intrarenal pressure was measured with a transurethral 7Fr ureteral occlusion balloon catheter and a urodynamic system during percutaneous renal access, rigid and flexible nephroscopy, and intracorporeal lithotripsy. Postoperative fever was correlated with elevated intrarenal pressure, stone type and surgical technique.
Enrolled in this study were 18 women and 13 men. Pressure greater than 30 mm. Hg was recorded in 8 patients (26%). Elevated pressure occurred under 2 conditions, namely incomplete positioning of the nephroscopy sheath within the collecting system and endoscopy through a narrow infundibulum. In 13 cases (42%) a fever of 38C or greater developed postoperatively. Elevated pressure did not correlate with fever. However, of those undergoing percutaneous nephrolithotomy for the removal of infection versus noninfection stones 64% and 24%, respectively, had fever postoperatively.
Renal intrapelvic pressure generally remains low during percutaneous nephrolithotomy. Elevated pressure was associated with incomplete nephroscopy sheath positioning within the collecting system and endoscopy through an infundibular narrowing. There was no association of renal pressure greater than 30 mm. Hg with fever but postoperative fever and percutaneous nephrolithotomy done for infection related stones correlated significantly.
含有细菌或内毒素的冲洗液发生全身吸收可能导致经皮肾镜取石术后发热和尿脓毒症。尽管据我们所知,确切的吸收方式尚不清楚,但肾盂内压力大于30 mmHg已被证明会导致肾盂静脉 - 淋巴管反流。我们在经皮肾镜取石术期间测量了肾盂内压力,并将压力与术后发热及手术技术相关联。
在经皮肾穿刺、硬性和软性肾镜检查以及体内碎石术期间,使用经尿道7Fr输尿管闭塞球囊导管和尿动力学系统测量肾内压力。术后发热与肾内压力升高、结石类型和手术技术相关。
本研究纳入18名女性和13名男性。8例患者(26%)记录到压力大于30 mmHg。压力升高出现在2种情况下,即肾镜鞘在集合系统内定位不完全以及通过狭窄的肾小盏进行内镜检查。13例患者(42%)术后出现38℃或更高的发热。压力升高与发热无关。然而,在因感染性结石与非感染性结石接受经皮肾镜取石术的患者中,术后发热的分别为64%和24%。
经皮肾镜取石术期间肾盂内压力通常保持较低。压力升高与肾镜鞘在集合系统内定位不完全以及通过肾小盏狭窄进行内镜检查有关。肾盂压力大于30 mmHg与发热无关,但术后发热与因感染相关结石进行的经皮肾镜取石术显著相关。