Pritchyk Keith M, Schiff Bradley A, Newkirk Kenneth A, Krowiak Edward, Deeb Ziad E
Department of Otolaryngology--Head and Neck Surgery, Georgetown University Medical Center, Washington, DC, USA.
Laryngoscope. 2002 Sep;112(9):1598-602. doi: 10.1097/00005537-200209000-00012.
The objectives of the study were to present four cases of renal cell carcinoma (RCC) metastatic to the head and neck, to recognize the appearance on radiographic studies, to understand the importance of preoperative embolization, and to review the results of treatment.
Retrospective review of patients diagnosed with metastatic RCC to the head and neck.
The records of four patients diagnosed with metastatic RCC at a tertiary medical center over a 5-year period from 1996 to 2001 were reviewed and analyzed for demographic and outcomes data.
Metastatic RCC to the head and neck was seen in the following locations: nasal cavity, lower lip, hard palate, tongue, and maxillary sinus. Presenting signs were loose upper molars, dysphagia, nasal obstruction, lower lip lesion, recurrent epistaxis, and foul nasal drainage. Histological studies confirmed metastasis of RCC in all four patients. Treatment consisted of preoperative radiation therapy, embolization, and local excision with adjunct chemotherapy.
Metastatic RCC to the head and neck is rare but can have serious consequences if not recognized before biopsy. We present several treatment options with local excision as the primary mode of treatment.
本研究的目的是呈现4例肾细胞癌（RCC）转移至头颈部的病例，识别影像学检查的表现，了解术前栓塞的重要性，并回顾治疗结果。
对诊断为RCC转移至头颈部的患者进行回顾性研究。
回顾并分析了1996年至2001年期间在一家三级医疗中心诊断为转移性RCC的4例患者的记录，以获取人口统计学和预后数据。
RCC转移至头颈部的部位如下：鼻腔、下唇、硬腭、舌和上颌窦。表现出的症状有上颌磨牙松动、吞咽困难、鼻塞、下唇病变、反复鼻出血和鼻腔恶臭分泌物。组织学研究证实所有4例患者均为RCC转移。治疗包括术前放射治疗、栓塞以及局部切除并辅助化疗。
RCC转移至头颈部较为罕见，但如果在活检前未被识别可能会产生严重后果。我们提出了几种以局部切除为主要治疗方式的治疗选择。
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