Lim Cathy, Chan Renee, Regan William
Department of Dermatology, Concord Hospital, Sydney, New South Wales, Australia.
Australas J Dermatol. 2005 Aug;46(3):158-60. doi: 10.1111/j.1440-0960.2005.00169.x.
An 86-year-old man presented with multiple papules on his face, neck, lips and ears 4 years after a left nephrectomy for renal cell carcinoma. Shave biopsies and excisions of the cutaneous lesions revealed findings consistent with metastatic renal cell carcinoma of clear cell type. The patient continued to present to the clinic over the next 3 years with similar eruptions, and biopsies continued to confirm renal cell carcinoma. During this time, metastases to the bone, lung, soft palate and posterior leg were also diagnosed. This case represents an unusual clinical presentation of metastatic renal cell carcinoma. It shows that a high index of suspicion should be maintained as cutaneous metastases can mimic other skin conditions.
一名86岁男性在因肾细胞癌行左肾切除术后4年,面部、颈部、嘴唇和耳部出现多个丘疹。对皮肤病变进行削切活检和切除后,发现结果与透明细胞型转移性肾细胞癌一致。在接下来的3年里,该患者继续因类似皮疹到诊所就诊,活检结果持续证实为肾细胞癌。在此期间,还诊断出骨、肺、软腭和小腿转移。该病例代表了转移性肾细胞癌一种不寻常的临床表现。它表明,由于皮肤转移可能模仿其他皮肤疾病,因此应保持高度的怀疑指数。