Chentsova N A, Gruntenko N E, Bogomolova E V, Adonyeva N V, Karpova E K, Rauschenbach I Yu
Institute of Cytology and Genetics, Russian Academy of Sciences, 10 Lavrentjev Avenue, Novosibirsk 630090, Russia.
J Comp Physiol B. 2002 Oct;172(7):643-50. doi: 10.1007/s00360-002-0293-9. Epub 2002 Aug 24.
Juvenile hormone hydrolysis, tyrosine decarboxylase activity, dopamine content and fitness (viability and fertility) were studied under normal and stress conditions in the adults of Drosophila melanogaster inactive strain carrying a mutation that decreases tyrosine decarboxylase activity and results in the lower contents of tyramine and octopamine. A sexual dimorphism of tyrosine decarboxylase activity, dopamine level and survival under heat stress in inactive flies was found. inactive adults showed higher dopamine levels and lower survival levels under heat stress as compared to wild type (Canton S) adults. Juvenile hormone degradation is decreased in young and increased in mature inactive females as compared to wild type. Fertility of the inactive strain did not differ from that of wild type strain under normal conditions, but after heat exposure the dynamics of its restoration was different. inactive females were found to develop the stress reaction, with juvenile hormone degradation, tyrosine decarboxylase activity, dopamine content and fertility levels used as the reaction indicators.
在正常和应激条件下，对携带降低酪氨酸脱羧酶活性并导致酪胺和章鱼胺含量降低的突变的黑腹果蝇无活性品系成虫的保幼激素水解、酪氨酸脱羧酶活性、多巴胺含量和适应性（活力和繁殖力）进行了研究。发现无活性果蝇中酪氨酸脱羧酶活性、多巴胺水平和热应激下的存活率存在性别二态性。与野生型（Canton S）成虫相比，无活性成虫在热应激下表现出更高的多巴胺水平和更低的存活率。与野生型相比，年轻无活性雌性的保幼激素降解减少，成熟无活性雌性的保幼激素降解增加。在正常条件下，无活性品系的繁殖力与野生型品系没有差异，但热暴露后其恢复动态不同。发现无活性雌性会产生应激反应，以保幼激素降解、酪氨酸脱羧酶活性、多巴胺含量和繁殖力水平作为反应指标。
