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短讯:一起涉及一名婴儿的马尔堡病毒病聚集性病例

Short communication: a cluster of Marburg virus disease involving an infant.

作者信息

Borchert Matthias, Muyembe-Tamfum Jean Jacques, Colebunders Robert, Libande Modeste, Sabue Mulangu, Van Der Stuyft Patrick

机构信息

Epidemiology Unit, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.

出版信息

Trop Med Int Health. 2002 Oct;7(10):902-6. doi: 10.1046/j.1365-3156.2002.00945.x.

Abstract

A noteworthy cluster of six cases of Marburg haemorrhagic fever (MHF) was identified in the Democratic Republic of Congo. One of the cases is the first infant Marburg fever patient ever documented. Three of six cases presented surprisingly mild symptoms. The results of epidemiological and virological investigations are compatible with person-to-person transmission through body fluids and with mother-to-child transmission while nurturing. The findings show that mild cases of MHF have to be expected during an outbreak and point out the difficulty to base patient management decisions on clinical case definitions alone.

摘要

在刚果民主共和国发现了值得关注的6例马尔堡出血热(MHF)病例群。其中1例是有记录以来首例感染马尔堡热的婴儿。6例中有3例症状出奇地轻微。流行病学和病毒学调查结果表明,该病可通过体液在人际间传播,也可在哺育期间发生母婴传播。研究结果表明,在疫情暴发期间可能会出现症状轻微的马尔堡出血热病例,同时也指出仅根据临床病例定义来做出患者管理决策存在困难。

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