péterfy F, Cserhidy J, Benkó A
Ann Immunol Hung. 1975;18:105-8.
The role of the immunizing dose on antibody production was studied in rabbits. The humoral immune response to soluble and insoluble human IgG was evaluated by the measurement of the amount of specific antibodies. The immobilizations of antigen was made by antigen-antibody precipitation and attachment of the protein to polyacrylamide and agarose matrices. It was found, that the antibody production did not decrease when the antigen dose was reduced from 100 microng to 300 microng; application of the antigen in immobilized form did not enhance the antibody response.
在兔子身上研究了免疫剂量对抗体产生的作用。通过测量特异性抗体的量来评估对可溶性和不溶性人IgG的体液免疫反应。抗原的固定通过抗原-抗体沉淀以及蛋白质与聚丙烯酰胺和琼脂糖基质的附着来实现。结果发现，当抗原剂量从100微克减少到300微克时，抗体产生并未减少；以固定形式应用抗原并未增强抗体反应。
