Marsh Brad J, Howell Kathryn E
Boulder Laboratory for 3D EM, Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado 80309, USA.
Nat Rev Mol Cell Biol. 2002 Oct;3(10):789-95. doi: 10.1038/nrm933.
Since the first description of the Golgi in 1898, key issues regarding this organelle have remained contentious among cell biologists. Resolving these complex debates, which revolve around Golgi structure-function relationships, is prerequisite to understanding how the Golgi fulfils its role as the central organelle and sorting station of the mammalian secretory pathway.
自1898年高尔基体首次被描述以来,关于这个细胞器的关键问题在细胞生物学家中一直存在争议。解决这些围绕高尔基体结构与功能关系的复杂争论,是理解高尔基体如何作为哺乳动物分泌途径的中心细胞器和分拣站发挥作用的先决条件。